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  • How common is merkel cell carcinoma
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    . Author manuscript; available in PMC: 2019 Mar 1.

    Published in final edited form as: J Am Acad Dermatol. 2017 Nov 2;78(3):457–463.e2.

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  • doi: 10.1016/j.jaad.2017.10.028

    Abstract

    Background

    Merkel cell carcinoma (MCC) incidence rates are rising and strongly age-associated, relevant for an aging population.

    Objective

    Determine MCC incidence in the United States and project incident cases through the year 2025.

    Methods

    Registry data were obtained from the SEER-18 database, containing 6,600 MCC cases.

    Age and sex-adjusted projections were generated utilizing US census data.

    Results

    Between 2000–2013, there was a 95% increase in the number of reported MCC cases, compared to 57% for melanoma and 15% for all ‘solid’ cancers.

    In 2013, the MCC incidence rate was 0.7 per 100,000 person-years in the US, corresponding to 2,488 cases. MCC incidence increased exponentially with age, from 0.1 to 1.0 to 9.8 (per 100,000 person-years) between age groups 40–44, 60–64, 85+ years, respectively.

    Due to aging of the “baby-boom” generation, US MCC incidence is predicted to climb to 2,835 cases

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